SOPHiA GENETICS Competitive Intelligence & Landscape
sophiagenetics.com ·
Overview
SOPHiA GENETICS Overview
The company's core product, the SOPHiA DDM™ platform, is a cloud-native, SaaS solution that analyzes multimodal data—including genomics, radiomics, clinical, biological, and digital pathology data—to generate actionable insights for hospitals, laboratories, and biopharma institutions. This platform helps clinicians and researchers interpret complex biological data to improve outcomes in cancer, rare diseases, and other medical conditions (ir.sophiagenetics.com). SOPHiA GENETICS serves over 780 healthcare institutions worldwide and also collaborates with biopharma companies for AI-powered drug discovery and development (Result 2).
The company’s mission is to democratize data-driven medicine by expanding access to AI and genomic insights globally, driven by a vision to make a lasting positive impact on healthcare. With a workforce of over 400 employees, SOPHiA GENETICS emphasizes innovation, collaboration, and improving scientific outcomes through its advanced AI capabilities and comprehensive data analysis solutions (Result 1; Result 6). Its value proposition centers on transforming healthcare by making complex biological data accessible and actionable for clinicians and researchers worldwide.
Competitors
SOPHiA GENETICS Competitors
Personalis, Inc. specializes in genomic profiling for cancer and immuno-oncology, emphasizing its comprehensive tumor profiling platform. Its market positioning is centered on providing high-precision genomic data to enable targeted therapies, which contrasts with SOPHiA's broader approach to healthcare data analytics (koalagains.com). While SOPHiA offers a decentralized platform, Personalis focuses on delivering detailed genomic insights for clinical decision-making, giving it a competitive edge in personalized cancer treatment.
Tempus AI, Inc. leverages artificial intelligence and big data analytics to deliver precision medicine solutions across oncology, cardiology, and infectious diseases. Its key differentiator is its extensive data ecosystem and AI-driven insights, which enable rapid, data-driven clinical decisions. Compared to SOPHiA, Tempus has a broader application scope and a strong emphasis on AI integration, positioning itself as a comprehensive health data platform (koalagains.com).
Illumina, Inc. is a giant in the genetic sequencing hardware market, with a dominant market share in sequencing instruments and consumables. Its market positioning is more hardware-centric, providing the foundational technology that powers many genomic applications. While SOPHiA focuses on data analytics and software solutions, Illumina's strength lies in its sequencing technology, which is often integrated into SOPHiA’s platform, making Illumina a key hardware partner rather than a direct competitor (koalagains.com).
Schrödinger, Inc. specializes in computational drug discovery using quantum mechanics and molecular simulations. Its market positioning is in the pharmaceutical R&D space, which is more indirect compared to SOPHiA's clinical data analytics. Schrödinger’s focus on drug development tools makes it a competitor in the broader biotech ecosystem, but its core offerings differ significantly from SOPHiA's healthcare analytics platform (koalagains.com).
Alternatives
SOPHiA GENETICS Alternatives
Product & Pricing
SOPHiA GENETICS Product and Pricing Intelligence
Their subscription models include a free trial offering limited features such as session recordings and post-session analytics, with paid plans like the Supercharge Basic and Enterprise tiers providing additional features such as automated notes, smart treatment plans, EHR integrations, and API access. The Basic plan costs $59/month or $468/year, with a discounted rate of $39/month or $390/year during limited-time offers, and includes 80 live sessions per month. The Enterprise plan is priced at $99/month or $948/year, with similar discounts, and offers advanced functionalities like in-session guidance and treatment planning (sophiahealth.ai).
Additionally, there is an Outcome Measurements Add-on available for $25/month or $10/month during promotional periods, which automates client assessments and progress tracking (sophiahealth.ai). Recent financial disclosures from SOPHiA GENETICS in 2026 reveal ongoing revenue growth and increased investment in scalable, AI-enhanced solutions, but specific recent changes to pricing strategies have not been explicitly detailed publicly (PR Newswire).
Sources
Pricing
sophiahealth.ai
SOPHiA GENETICS DDM™ Platform
marketplace.microsoft.com
SOPHiA GENETICS - Democratizing Data-Driven Medicine, Together
sophiagenetics.com
SOPHiA GENETICS Reports Fourth Quarter and Full Year 2025 Results
prnewswire.com
SOPHiA GENETICS Reports Fourth Quarter and Full Year 2025 Results
www2.prnewswire.com
Hiring & Layoffs
SOPHiA GENETICS Hiring and Layoffs
In addition, the company announced a major expansion in the United States in February 2026, signing agreements with two significant health systems, which signals a focus on scaling its operations and integrating more deeply into the healthcare ecosystem (SOPHiA GENETICS News). There is no publicly available information on layoffs, suggesting that SOPHiA GENETICS is currently prioritizing growth and talent acquisition to support its strategic initiatives. Overall, these hiring patterns and expansion efforts indicate a company strategy centered on technological innovation, geographic expansion, and strengthening its position as a leader in data-driven healthcare solutions.
Sources
SOPHiA GENETICS Careers, Perks + Culture
builtin.com
34 Sophia Genetics Jobs in Worldwide
linkedin.com
SOPHiA GENETICS Announces Major Expansion in the United States with the Signing of Two Major Integrated Health Systems - SOPHiA GENETICS
sophiagenetics.com
Bring your learning to life - Career - SOPHiA GENETICS
careers.sophiagenetics.com
SOPHiA GENETICS Careers, Perks + Culture | Built In
builtin.com
SOPHiA GENETICS hiring for Bioinformatician (12 Month Contract)
jobs.weekday.works
Leadership
SOPHiA GENETICS Management and Leadership Team
In terms of recent leadership hires, SOPHiA GENETICS appointed Kevin Puylaert as Chief Sales Officer in January 2026, reflecting ongoing efforts to bolster commercial leadership (Simply Wall St). The company also promoted Ross Muken to President in November 2024, and earlier, in 2022, it added key executives like Peter Casasanto as Chief BioPharma Officer and Abhimanyu Verma as Chief Technology Officer to enhance its focus on the pharmaceutical industry (PR Newswire).
Furthermore, recent updates highlight a strategic leadership transition with Muken’s promotion and the appointment of George Cardoza, indicating a focus on strengthening executive management to support the company's growth and innovation strategies (SOPHiA GENETICS). This evolving leadership structure underscores SOPHiA GENETICS' commitment to maintaining its position as a leader in data-driven medicine and genomic analysis.
Sources
SOPHiA GENETICS SA (SOPH) Leadership & Management Team ...
simplywall.st
Executive Team Hires at SOPHiA GENETICS to Enhance BioPharma Business - Jan 10, 2022
ir.sophiagenetics.com
SOPHiA GENETICS, Inc. - Corporate Governance Overview
ir.sophiagenetics.com
SOPHiA GENETICS Provides Preliminary Fourth Quarter and Full ...
sophiagenetics.com
SOPHiA GENETICS Provides Preliminary Fourth Quarter and Full ...
prnewswire.com
SOPHiA GENETICS Promotes Ross Muken to President and Appoints George Cardoza as Chief Financial Officer
prnewswire.com
Financials
SOPHiA GENETICS Financial Performance, Fundraising, M&A
In terms of profitability, SOPHiA GENETICS experienced net losses in 2025, with an IFRS net loss of $79 million, which increased by 26% compared to the previous year. Despite these losses, the company demonstrated operational growth through increased analysis volume, performing over 391,000 analyses in 2025, a new record (PRNewswire).
Regarding fundraising and valuation, SOPHiA GENETICS had a valuation of approximately $268 million based on valuation multiples, with a reported revenue of $81 million in the last twelve months and an EBITDA of around -$40 million, reflecting its growth stage and ongoing investments (multiples.vc). The company has also been active in M&A and strategic partnerships, leveraging its AI-driven platform to expand its market presence and capabilities (sophiagenetics.com). Overall, SOPHiA GENETICS continues to demonstrate solid revenue growth and operational scale despite ongoing net losses, positioning it as a key player in the precision medicine sector.
Sources
SOPHiA GENETICS Provides Preliminary Fourth Quarter and Full ...
ir.sophiagenetics.com
SOPHiA Genetics - Multiples.vc - Public Comps and Valuation Multiples
multiples.vc
SOPHiA GENETICS Provides Preliminary Fourth Quarter and Full ...
sophiagenetics.com
SOPHiA GENETICS Reports Fourth Quarter and Full Year 2025 ...
finance.yahoo.com
SOPH Stock Forecast: Analyst Ratings, Predictions & Price Target 2026
public.com
SOPHiA GENETICS Reports Fourth Quarter and Full Year 2025 Results
prnewswire.com
SOPHiA GENETICS Reports Fourth Quarter and Full Year 2025 Results (2026-03-03) | Seeking Alpha
seekingalpha.com
Investor Relations | SOPHiA GENETICS, Inc. - News
ir.sophiagenetics.com
Partnerships
SOPHiA GENETICS Partnerships, Clients and Vendors
In terms of strategic alliances, SOPHiA GENETICS has partnered with industry leaders like QIAGEN, integrating their cloud-based platform with QIAGEN’s next-generation sequencing panels, which allows customers to order combined solutions for genomic analysis (corporate.qiagen.com). Additionally, their collaboration with Complete Genomics involves integrating sequencing and AI analytics to accelerate the adoption of precision medicine, further expanding their technological ecosystem (sophiagenetics.com).
SOPHiA GENETICS also maintains partnerships with pharmaceutical companies such as AstraZeneca, expanding AI-driven collaborations to improve patient outcomes in diseases like breast cancer (sophiagenetics.com). These relationships highlight their role in integrating AI, cloud technology, and sequencing platforms within a broad ecosystem that supports clinical and research applications across the healthcare industry (sophiagenetics.com).
Sources
SOPHiA GENETICS Announces Major Expansion in the United ...
sophiagenetics.com
SOPHiA GENETICS expands collaboration with AstraZeneca using AI to improve breast cancer patient outcomes - SOPHiA GENETICS
sophiagenetics.com
SOPHiA GENETICS and Complete Genomics Integrate Sequencing and AI Analytics to Accelerate Adoption of Precision Medicine - SOPHiA GENETICS
sophiagenetics.com
SOPHiA GENETICS Provides Preliminary Fourth Quarter and Full ...
ir.sophiagenetics.com
QIAGEN and SOPHiA GENETICS forge partnership to combine ...
corporate.qiagen.com
Events
SOPHiA GENETICS Event Participations
In addition to investor-focused events, SOPHiA GENETICS engages in scientific and medical conferences. For instance, they announced updates on SOPHiA UNITY at ESMO 2024, a global oncology research initiative, demonstrating their involvement in major medical congresses that focus on cancer research and precision medicine (ir.sophiagenetics.com).
While specific details on webinars and community events are not extensively documented, the company's participation in high-profile healthcare events and strategic conferences highlights their active role in fostering innovation, collaboration, and knowledge sharing within the healthcare and genomics sectors.
Sources
Events - Investor Relations | SOPHiA GENETICS, Inc.
ir.sophiagenetics.com
SOPHiA GENETICS Announces Updates on SOPHiA UNITY at ...
ir.sophiagenetics.com
Sophia Genetics - Wikipedia
en.wikipedia.org
SOPHiA GENETICS Unveils Strategy to Drive Health Care ...
ir.sophiagenetics.com
News - Investor Relations | SOPHiA GENETICS, Inc.
ir.sophiagenetics.com
Frequently Asked Questions
Who are SOPHiA GENETICS's main competitors in the precision medicine space?
SOPHiA GENETICS faces competition from companies like Guardant Health (specializing in liquid biopsies), Personalis (genomic profiling for cancer), Tempus AI (AI-driven precision medicine across multiple diseases), Illumina (genetic sequencing hardware), and Schrödinger (computational drug discovery).
How can I monitor SOPHiA GENETICS's strategic moves and market activity?
Staying informed about SOPHiA GENETICS involves monitoring their press releases, investor relations events (like earnings calls), participation in industry conferences such as ESMO, and tracking their hiring activity. Tools like ForesightIQ automate this process by monitoring SOPHiA GENETICS's digital exhaust, including job postings, website changes, and more, to surface strategic signals.
What kind of competitive intelligence sources are most valuable for tracking SOPHiA GENETICS?
Valuable competitive intelligence sources include SOPHiA GENETICS's investor relations website, LinkedIn (for hiring patterns), news publications covering their partnerships and expansions, and scientific conference proceedings. Analyzing these sources can reveal insights into their technology roadmap, market strategy, and financial performance.
How does SOPHiA GENETICS compare to Tempus AI in terms of market approach?
While both SOPHiA GENETICS and Tempus AI utilize AI in healthcare, SOPHiA GENETICS focuses on a decentralized, cloud-native platform for genomic and radiomic data analysis. Tempus AI, on the other hand, has a broader application scope across oncology, cardiology, and infectious diseases, with a stronger emphasis on integrating AI into a comprehensive health data platform.
Is SOPHiA GENETICS currently hiring, and what does this indicate about their strategy?
Yes, SOPHiA GENETICS is actively hiring across various departments, including engineering, AI/ML, and sales, with a focus on the US, Europe, and Switzerland. This hiring activity, coupled with recent expansions in the US, suggests a growth-oriented strategy centered on technological innovation and geographic expansion.
What market signals might indicate SOPHiA GENETICS's next strategic move?
Key market signals to watch include significant partnerships with healthcare systems or pharmaceutical companies, new product announcements or platform updates (especially related to SOPHiA DDM™), changes in executive leadership, and shifts in hiring priorities. ForesightIQ can help identify these signals by continuously monitoring SOPHiA GENETICS's online presence.
What are some alternatives to SOPHiA GENETICS's SOPHiA DDM™ platform?
Alternatives to SOPHiA DDM™ include Lifebit (federated research platform), InheriNext by CompassBioinformatics (inherited disease analysis), Helena Bioinformatics (AI-powered variant interpretation), and Franklin by Genoox (comprehensive WGS workflow).
What is SOPHiA GENETICS's pricing model for their SOPHiA DDM™ platform?
While SOPHiA GENETICS does not publicly disclose detailed pricing, they appear to focus on scalable, enterprise-level solutions for large healthcare networks and biopharma institutions. Their pricing model likely involves subscriptions with features like automated notes, EHR integrations, and API access.
What can SOPHiA GENETICS's partnership strategy reveal about its future direction?
SOPHiA GENETICS's partnerships, such as those with QIAGEN, Complete Genomics, and AstraZeneca, highlight their focus on integrating AI, cloud technology, and sequencing platforms. These alliances indicate a strategy to expand their ecosystem and enhance their capabilities in precision medicine and genomic analysis.
Who is the current CEO of SOPHiA GENETICS and has there been any recent leadership changes?
While Dr. Jurgi Camblong was the co-founder and CEO for a long time, Ross Muken was promoted to CEO, effective July 1, 2026. George Cardoza has also been appointed as the new CFO.
How does Guardant Health's market focus compare to SOPHiA GENETICS?
Guardant Health is primarily focused on liquid biopsy and non-invasive cancer diagnostics, giving them a specialized position in precision oncology. SOPHiA GENETICS, while also active in oncology, has a broader approach to healthcare data analytics across various diseases and applications.
What type of events does SOPHiA GENETICS participate in to promote its platform and solutions?
SOPHiA GENETICS actively participates in events like investor relations meetings (earnings calls, investor days) and scientific/medical conferences such as ESMO. These events serve to showcase their platform, announce strategic partnerships, and engage with the healthcare and genomics communities.
Powered by ForesightIQ · Competitive intelligence from digital exhaust